Two sample MR report
FAM3B_Dendritic Cell (DC) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0944776 | 0.1441754 | 0.6307036 |
| Weighted median | 3 | -0.0332821 | 0.0150491 | 0.0269963 |
| Inverse variance weighted | 3 | -0.0283780 | 0.0116818 | 0.0151305 |
| Simple mode | 3 | -0.0367913 | 0.0184089 | 0.1836999 |
| Weighted mode | 3 | -0.0366046 | 0.0185771 | 0.1875899 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.319852 | 1 | 0.2506187 |
| Inverse variance weighted | 1.599699 | 2 | 0.4493967 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0943976 | 0.2050044 | 0.7252837 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.59e-05 | 0 | TRUE | 0.5218523 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
